[PDF] Proteins And Proteomics Of Leishmania And Trypanosoma

Proteins and Proteomics of Leishmania and Trypanosoma PDF
Author: André L.S. Santos
Publisher: Springer Science & Business Media
ISBN: 9400773056
Size: 77.27 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 381
View: 4754

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Proteins And Proteomics Of Leishmania And Trypanosoma

by André L.S. Santos, release date 2013-11-22, Proteins And Proteomics Of Leishmania And Trypanosoma Books available in PDF, EPUB, Mobi Format. Download Proteins And Proteomics Of Leishmania And Trypanosoma books, This book contains a collection of critical reviews on the expression of biologically functional proteins in Leishmania and Trypanosoma, which was written by renowned researchers on this field. Species belonging to these trypanosomatids’ genera are etiological agents of leishmaniasis, Chagas’ disease and sleeping sickness that are extremely debilitating human infection diseases, which remain a major health problem especially in countries from Latin America, Africa and Middle East. Substantiating the problem, the currently accepted drugs for these diseases are quiet unsatisfying due to their low efficacy and high toxicity. In order to solve these real problems, several research groups around the world have become involved in the study and identification of novel potential targets in the trypanosomatid cell. Since proteins are key macromolecules involved in crucial metabolic processes of all living cells, studies have focused on the expression of specific proteins produced by Leishmania and Trypanosoma by means of different biochemical, molecular and proteomic approaches in order to explore them as targets for understanding the parasite life cycle and developing new strategies against trypanosomiasis. With these proposals in mind, the book “Proteins and Proteomics of Leishmania and Trypanosoma” encompasses (i) an integrated view about the biochemistry of parasites belonging to the Leishmania and Trypanosoma genera; (ii) an updated review on the expression of biologically relevant proteins by human pathogenic trypanosomatids and their possible role in the interaction with host cells/molecules as well as a target for development of both alternative chemotherapies and vaccine; and (iii) several pictures, diagrams and tables that can be used to illustrate both undergraduate and postgraduate teaching as well as scientific lectures, being a useful resource for students and researchers.




[PDF] Leishmaniasis From Innate And Adaptive Immunity To Vaccine Development

Leishmaniasis  From Innate and Adaptive Immunity to Vaccine Development PDF
Author: Heinrich Korner
Publisher: Frontiers Media SA
ISBN: 2889633004
Size: 18.86 MB
Format: PDF, ePub, Mobi
Category :
Languages : en
Pages :
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Leishmaniasis From Innate And Adaptive Immunity To Vaccine Development

by Heinrich Korner, release date 2020-01-10, Leishmaniasis From Innate And Adaptive Immunity To Vaccine Development Books available in PDF, EPUB, Mobi Format. Download Leishmaniasis From Innate And Adaptive Immunity To Vaccine Development books, The parasitic disease leishmaniasis in its various clinical manifestations from self-resolving skin lesion to deadly systemic infection is a serious health problem in many developing countries and is considered to be a neglected tropical disease by the World Health Organization. To date, a vaccine is lacking and strategies to treat severe forms of leishmaniasis efficiently are missing. Basic research using animal models of experimental visceral or cutaneous leishmaniasis has allowed to dissect the immune response to parasitic pathogens and has contributed substantially to many important, paradigm-changing insights such as the role of cytokines in helper T-cell differentiation and the impact of myeloid cell subsets on innate and adaptive immunity. One strength of experimental leishmaniasis is that tissue-associated parasites constitute a self-renewing antigen reservoir that needs to be controlled by adaptive and innate branches of the immune response. Therefore, mechanisms involved in wound healing, chronic inflammation, host pathogen interactions and the development of long lasting memory responses can be interrogated. This research topic aims to cover a broad range of important concepts in adaptive and innate immunity to leishmaniasis and will include recent work, including vaccine development, to understand and fight this tropical disease. We welcome both reviews and original research articles that cover the latest breakthroughs in leishmaniasis research. We recognize that reproducibility is a fundamental aspect of research and thus welcome also confirmatory studies.




[PDF] Comparative Genomics And Proteomics In Drug Discovery

Comparative Genomics and Proteomics in Drug Discovery PDF
Author: John Parrington
Publisher: Taylor & Francis
ISBN: 1134155158
Size: 28.59 MB
Format: PDF, ePub, Docs
Category : Science
Languages : en
Pages : 164
View: 7621

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Comparative Genomics And Proteomics In Drug Discovery

by John Parrington, release date 2018-11-01, Comparative Genomics And Proteomics In Drug Discovery Books available in PDF, EPUB, Mobi Format. Download Comparative Genomics And Proteomics In Drug Discovery books, Comparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programs, and in particular the key role that comparative genomics and proteomics play within this strategy. Each chapter is written by respected authorities, with hands-on experience, from both academic and pharmaceutical backgrounds.




[PDF] Trypanosomes And Trypanosomiasis

Trypanosomes and Trypanosomiasis PDF
Author: Stefan Magez
Publisher: Springer Science & Business Media
ISBN: 3709115566
Size: 27.27 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 294
View: 1592

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Trypanosomes And Trypanosomiasis

by Stefan Magez, release date 2013-09-24, Trypanosomes And Trypanosomiasis Books available in PDF, EPUB, Mobi Format. Download Trypanosomes And Trypanosomiasis books, This new volume written by experts in the field of trypanosome research covers every aspect of trypanosome-vector-host biology. It is a must read for basic researchers working with trypanosomes and related organisms, infection and drug development as well as parasitology in a broader sense. ​




[PDF] Immunobiology Of Leishmaniasis

Immunobiology of Leishmaniasis PDF
Author: Herbert Leonel de Matos Guedes
Publisher: Frontiers Media SA
ISBN: 288966029X
Size: 54.22 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages :
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Immunobiology Of Leishmaniasis

by Herbert Leonel de Matos Guedes, release date 2020-09-18, Immunobiology Of Leishmaniasis Books available in PDF, EPUB, Mobi Format. Download Immunobiology Of Leishmaniasis books,




[PDF] Issues In Immunology Research 2011 Edition

Issues in Immunology Research  2011 Edition PDF
Author:
Publisher: ScholarlyEditions
ISBN: 1464964041
Size: 75.27 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 1986
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Issues In Immunology Research 2011 Edition

by , release date 2012-01-09, Issues In Immunology Research 2011 Edition Books available in PDF, EPUB, Mobi Format. Download Issues In Immunology Research 2011 Edition books, Issues in Immunology Research / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immunology Research. The editors have built Issues in Immunology Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immunology Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Immunology Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.




[PDF] Drug Targets In Kinetoplastid Parasites

Drug Targets in Kinetoplastid Parasites PDF
Author: Hemanta K. Majumder
Publisher: Springer Science & Business Media
ISBN: 0387775706
Size: 22.55 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 158
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Drug Targets In Kinetoplastid Parasites

by Hemanta K. Majumder, release date 2008-09-15, Drug Targets In Kinetoplastid Parasites Books available in PDF, EPUB, Mobi Format. Download Drug Targets In Kinetoplastid Parasites books, The dreaded protozoal diseases caused by a number of Kinetoplastid parasites threaten mankind, as therapeutic tools for the treatment of most parasitic diseases are extremely limited. Development of commercially available vaccines is still far from reality, though research and trial programs continue. This book covers current research into drug therapeutics for the conditions caused by the parasites, which if viewed globally, pose an increasing threat to human health and welfare.




[PDF] Clinical Proteomics

Clinical Proteomics PDF
Author: Jennifer E. Van Eyk
Publisher: Wiley-Blackwell
ISBN:
Size: 52.28 MB
Format: PDF, ePub, Docs
Category : Science
Languages : en
Pages : 659
View: 2131

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Clinical Proteomics

by Jennifer E. Van Eyk, release date 2008-01-14, Clinical Proteomics Books available in PDF, EPUB, Mobi Format. Download Clinical Proteomics books, Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases. Following an overview of clinical proteomics, the authors look at the technologies available, before moving on to cancer, cardiopulmonary disease, diabetes and stroke. A whole section is devoted to toxicity and the work is rounded off with a discussion of the future of clinical proteomics.




[PDF] Encyclopedia Of Genetics Genomics Proteomics And Bioinformatics 8 Volume Set

Encyclopedia of Genetics  Genomics  Proteomics and Bioinformatics  8 Volume Set PDF
Author: Michael J. Dunn
Publisher: Wiley
ISBN: 9780470849743
Size: 52.36 MB
Format: PDF, ePub, Docs
Category : Science
Languages : en
Pages : 4096
View: 2844

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Encyclopedia Of Genetics Genomics Proteomics And Bioinformatics 8 Volume Set

by Michael J. Dunn, release date 2005-11-11, Encyclopedia Of Genetics Genomics Proteomics And Bioinformatics 8 Volume Set Books available in PDF, EPUB, Mobi Format. Download Encyclopedia Of Genetics Genomics Proteomics And Bioinformatics 8 Volume Set books, Available in print and online, this unique reference brings together all four fields of genetics, genomics, proteomics, and bioinformatics to meet your dynamic research requirements. It brings together the latest concepts in these vibrant areas and ensures a truly multidisciplinary approach. Topics include genetic variation and evolution, epigenetics, the human genome, expression profiling, proteome families, structural proteomics, gene finding/gene structure, protein function and annotation, and more. The work incorporates a vast amount of topical information, profiles cutting-edge techniques, and presents the very latest findings from an international team of over five hundred contributors. With articles for both students and more experienced scientists, this is a key reference source for everyone. Contains more than 450 articles covering all aspects of genomics, proteomics, bioinformatics and related technologies Includes a glossary containing over 550 clear and concise definitions "I am pleased to recommend it heartily as a essential reference tool…should remain the definitive work…for many years to come." THE CHEMICAL EDUCATOR “Jorde…and co-editors have done a remarkable job in coordinating this information, distilling it into a package that is both easy to navigate and over-flowing in discovery." ELECTRIC REVIEW